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“I took magic truffles and felt nothing.” It happens more often than you’d think, and in almost every case there’s a clear reason. Before you conclude that your truffles don’t work, go through this checklist. It covers the most common causes we see in our customer service, and how to get it right next time.
In short: the most common reasons are tolerance (from earlier use, even days before), taking more on the same day, not chewing well, a full stomach, a dose that’s too low for your weight or variety, not waiting long enough, or certain medication. Psilocybin tolerance builds very fast, so a second portion the same day usually does almost nothing.
1. Tolerance: you used psilocybin recently
Psilocybin tolerance builds up quickly. After a trip (or several days of microdosing), the same dose has much less effect for days afterwards. This is the number one reason for “no effect” when someone took truffles again within a week or two. Read more in our tolerance guide.
2. You took more on the same day
If the first portion didn’t do much and you take another (larger) one a few hours later, the second portion will often also do little: tolerance already kicks in within hours. Taking 15 g and then 30 g on the same day doesn’t add up to a strong trip; it usually just wastes truffles. Wait at least two weeks and try again with one well-chosen dose.
3. You didn’t wait long enough
Effects usually start 20–60 minutes after eating, but can take longer, especially when swallowed whole or after a meal. Wait at least 90 minutes before concluding anything. See our trip timeline.
4. You didn’t chew (well)
Truffles are firm. Chewing them thoroughly releases the active compounds; swallowing pieces whole can delay and weaken the effect. See how to take magic truffles.
5. Your stomach was full
A heavy meal right before slows absorption and can make the effect weaker and less predictable. For a full dose, eat light and take the truffles a few hours after your last proper meal.
6. The dose was too low for you or the variety
Body weight and variety both matter. A dose that’s strong on Hollandia can be mild on Mexicana. Check the dosage guide and our calculator, which takes the variety into account. And remember: everyone is different; some people simply need a bit more.
7. Medication
Some antidepressants (such as SSRIs) can strongly reduce the effect of psilocybin. Combining psilocybin with psychoactive medication is not recommended at all. Never stop medication to take truffles; talk to your doctor.
8. Storage
Truffles that were kept warm, opened for days, or used well past their shelf life lose quality and strength. Keep them sealed in the fridge and use them within their shelf life. See how to store magic truffles.
9. Expectations and setting
At low doses, effects can be subtle: a lighter mood, brighter colours, giggles. If you expected strong visuals, it may feel like “nothing”. Also a tense or busy setting can mask the effects.
What about microdosing?
With a microdose you’re not supposed to feel much. That’s the point. Read what a microdose feels like.
Checklist for next time
- ☐ No psilocybin in the past 2 weeks
- ☐ One portion, taken at once; no topping up within 90 minutes
- ☐ Chewed thoroughly
- ☐ Light stomach (no heavy meal beforehand)
- ☐ Dose checked for your weight and variety
- ☐ No interfering medication
- ☐ Truffles stored in the fridge, sealed, within shelf life
- ☐ Calm, comfortable setting
Still no effect?
If you followed all of this and still felt nothing, contact us at info@awake-shop.com with your order number, the variety, how much you took and when, your body weight, and whether you used psilocybin or medication recently. We’ll look into it with you.
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Questions?
Check our FAQ or email us at info@awake-shop.com. We’re happy to help.
Medical disclaimer: this guide is for educational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis or treatment. Always consult a qualified healthcare professional for any changes to your diet, exercise routine or medication, and never disregard professional medical advice because of something you read here. Do not use psilocybin if you are under 18, pregnant or breastfeeding, take medication such as SSRIs or other antidepressants, or have (a history of) serious mental health conditions. Effects differ per person; we don’t promise specific results.
